Lower Extremity Arterial Disease Doctor in Los Angeles

Lower extremity arterial disease treatment

Do you have lower extremity arterial disease? Learn what it is, how to spot symptoms, and your treatment options in this quick overview from lower extremity arterial disease doctor Michael Lalezarian. He performs lower extremity arterial disease treatment in the Los Angeles area.

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Lower Extremity Arterial Disease Doctor
Risk Factors of Lower Extremity Arterial Disease
Symptoms of Lower Extremity Arterial Disease
Diagnosing Lower Extremity Arterial Disease
Lower Extremity Arterial Disease Treatment
Lower Extremity Arterial Disease Surgery

Lower extremity arterial disease doctor Michael Lalezarian in Los Angeles, California

Lower Extremity Arterial Disease Doctor

Dr. Michael Lalezarian

Find the care you need for lower extremity arterial disease. Dr. Michael Lalezarian is a double-board certified Vascular Interventional Radiologist specializing in minimally invasive arterial disease treatment. He is a committed partner in the battle against the devastating consequences of advanced peripheral arterial disease (PAD) and critical limb ischemia (CLI).
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“I want to start by thanking Dr Lalezarian for everything. He has changed my life and my legs are no longer in pain. I have no words to thank you and thank you to the girls for being so kind and helpful.” Juan O, December 2023

What is Lower Extremity Arterial Disease?

Lower extremity arterial disease, often called peripheral artery disease (PAD), is a condition that develops when the arteries in the legs and feet become narrowed or blocked by atherosclerosis. Atherosclerosis is a systemic vascular condition that is characterized by the accumulation of a fatty substance called plaque, which builds up on the inside walls of the arteries. This narrowing is also referred to as stenosis. As the arteries narrow, blood flow is restricted, eventually causing an insufficient supply of blood to the muscles and tissues in the legs and feet. In turn, insufficient blood supply can cause leg pain, poor healing, ulceration, and even gangrene in the most severe cases. Individuals with lower extremity arterial disease often have other cardiovascular problems caused by atherosclerosis, such as coronary artery disease. Depending on the severity of your lower extremity arterial disease, your vascular specialist may also mention critical limb ischemia and/or arterial ulceration. Critical limb ischemia develops when lower extremity arterial disease is left untreated. Blood flow through the leg becomes so restricted that pain is experienced at rest. Ulceration and gangrene are also common at this stage. Amputation may be required if less invasive treatments are not able to restore blood flow or ‘salvage’ the limb. Arterial ulcers can develop where blood supply is most limited, usually at the farthest parts of the body such as feet, toes, side of the ankle, or areas of pressure to the skin. Arterial ulcers are also indicative of late-stage lower extremity arterial disease and often require intervention to heal.

Risk Factors of Lower Extremity Arterial Disease

For the vast majority of affected individuals, lower extremity arterial disease is a lifestyle condition. Several years of smoking, high blood pressure, uncontrolled diabetes, high cholesterol, obesity, and/or sedentary lifestyle can lead to lower extremity arterial disease. Increasing age (over 50) and family history of atherosclerosis also put you at increased risk of developing lower extremity arterial disease. Addressing these risk factors with lifestyle modifications – i.e. quitting smoking, improving diet, exercising – is critical in reversing the early stages of lower extremity arterial disease before intervention is required. However, because lower extremity arterial disease develops over many years, many patients do not recognize their symptoms until it is too late.
Lower extremity arterial disease chart

Lower Extremity Arterial Disease Symptoms

Do you experience cramping pain in your legs or buttocks after walking long distances? This is one of the most telling signs of lower extremity arterial disease, and it tends to get worse if left untreated. Review these lower extremity arterial disease symptoms to learn if you might have it.

Leg Discomfort: Generalized leg discomfort should be cause for alarm in diabetics, smokers, and the elderly. Leg pain is certainly not specific to lower extremity arterial disease, but it may be the first sign that vascular issues are present.

Claudication: Claudication describes a cramping pain that is felt in the hips, thighs, buttocks, calves, or feet during exercise that then subsides when resting. This is the most telling symptom of lower extremity arterial disease and should be taken very seriously.

Cold Feet: Lack of blood flow and poor vascularity can render the lower extremity exceptionally cold. Cold feet can indicate lower extremity arterial disease, especially when one foot is significantly colder than the other.

Weak Pulse: A simple pulse check can be very telling. A weak or absent pulse at the groin, behind the knee, on the inner ankle, or on the top of the foot can indicate lower extremity arterial disease.

Rest Pain: Pain may persist even when sitting or lying down. This pain typically affects the forefoot and toes. By the time patients experience rest pain, it is likely that lower extremity arterial disease has progressed to an advanced stage.

Tissue Loss: Tissue loss occurs when tissue in the leg or the foot does not have an adequate blood supply. This can present as skin color changes, open wounds, and sores. Tissue loss is a late-stage symptom of lower extremity arterial disease.

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Man in Los Angeles experiencing lower extremity arterial disease symptoms

Diagnosing Lower Extremity Arterial Disease

Diagnosis of lower extremity arterial disease typically starts with a screening of your risk factors, and is followed up with specialized diagnostic techniques to understand the health of the arteries in your legs. Screening: Lower extremity peripheral arterial disease screening is recommended for everyone that meets certain risk factors, the most common of which include being over the age of 65, history of diabetes, history of smoking, or history of another atherosclerotic cardiovascular condition. Ankle-Brachial Index: The ankle-brachial index (ABI) is one of the most common screening methods for lower extremity arterial disease. ABI is used to assess how well blood is flowing in the legs by measuring blood pressure in the ankles and comparing it to blood pressure in the arms. Imaging: In the hands of a trained technician, ultrasound can help pinpoint the location and severity of lower extremity arterial disease, while advanced vascular imaging techniques such as CTA, MRA, and contrast arteriography can provide rich detail on arterial flow and blockages. Angiogram: An angiogram is a diagnostic imaging test used to examine blood vessels throughout the body and detect blockages, enlargements, clots, or malformations. An angiogram is obtained by injecting contrast dye into the vessels using a long, flexible catheter, typically inserted through a small puncture in the groin. The dye enhances visibility, allowing the blood vessels to appear clearly on X-ray images. It’s common for lower extremity arterial disease to be diagnosed and treated within the same angiography procedure, combining the angiogram with minimally invasive treatments such as balloon angioplasty, stenting, or atherectomy, as described below.
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Lower extremity peripheral arterial disease angiogram
Lower extremity arterial angiogram to visualize the arteries in the leg.

Lower Extremity Arterial Disease Treatment

Lower extremity arterial disease treatments include lifestyle changes, medications, minimally invasive procedures, and invasive surgical options. Review your options below. 

Lifestyle & Medications

Patients whose symptoms are mild to moderate can often manage their disease by making lifestyle changes such as quitting smoking, improving diet, and getting regular exercise. It’s also important to work with your doctor(s) to manage related conditions, such as diabetes, hypertension, and high cholesterol. Your doctor may also prescribe blood-thinning drugs or other firstline medications to help control the progression of lower extremity arterial disease. 

Minimally Invasive Treatment

When lower extremity arterial disease is severe enough to warrant interventional treatment, the goal is to open blocked vessels and re-establish blood flow throughout the legs and feet. At ProVascularMD, we have extensive experience in lower extremity arterial treatments including balloon angioplasty, stenting, and atherectomy. We also partner with our colleagues in wound care, podiatry, endocrinology, vascular surgery, and other specialties that are essential to healing the lower extremities. Learn more about the lower extremity arterial disease treatments that we offer below.

Balloon Angioplasty: Balloon angioplasty involves threading a wire through the narrowed or blocked artery along the length of the blood vessel. A deflated balloon is placed over the wire and then inflated, opening the blockage and allowing blood to flow more freely through the treated artery.

Stenting: Stenting involves the placement of a small tubular device that holds the artery open, often immediately after balloon angioplasty is performed. The goal of stenting is to prevent the artery from closing again and to help maintain healthy blood flow.

Atherectomy: Atherectomy devices cut through or shave away tough plaque in the artery, not unlike a drill or a sanding device. Atherectomy is typically reserved for totally occluded arteries or arteries with hard, calcified plaques that are unsafe to open with balloon angioplasty alone. 

Surgery for Lower Extremity Arterial Disease

When minimally invasive treatment is not an option, you may be referred to a vascular surgeon for surgery for lower extremity arterial disease. Bypass surgery and endarterectomy are two of the more common, last-option treatments for lower extremity arterial disease.

Bypass Surgery: Bypass surgery can be used to re-establish blood flow between a proximal artery (closer to the heart) and one that’s more distal (farther from the heart) by grafting in a vessel. Bypass surgery is often used when minimally invasive treatment is not possible.

Endarterectomy: Endarterectomy is the surgical removal of part of the inner lining of the artery along with any plaque deposits that may be obstructing the vessel. Endarterectomy is a common approach to lower extremity arterial disease when minimally invasive treatment is not possible.

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More Resources
Lower Extremity Arterial Disease

Lower Extremity Arterial Disease

Learn what it is, how to spot symptoms, and your treatment options in this quick overview.
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Signs and symptoms of arterial ulcers, and how to treat them.
Los Angeles Vascular Specialist Dr. Michael Lalezarian

Vascular Specialist in Los Angeles

Learn more about Los Angeles Vascular Specialist Dr. Michael Lalezarian.

References [1] Berger, JS., Davies, MG. Overview of lower extremity peripheral artery disease (Beyond the Basics). UptoDate. Accessed November 2020. [2] Berger, JS., Newman, JD. Overview of peripheral artery disease in patients with diabetes mellitus. UptoDate. Accessed November 2020. [3] Emdin CA, Anderson SG, Callender T, et al. Usual blood pressure, peripheral arterial disease, and vascular risk: cohort study of 4.2 million adults. BMJ. 2015;351:h4865. Published 2015 Sep 29. [4] Harris, L. Epidemiology, risk factors, and natural history of lower extremity peripheral artery disease. UptoDate. Accessed November 2020. [5] Hayward, RA.Screening for lower extremity peripheral artery disease. UptoDate. Accessed November 2020. [6] Mills, JL. Classification of acute and chronic lower extremity ischemia. UptoDate. Accessed November 2020. [7] Neschis, DG., Golden, MA. Clinical features and diagnosis of lower extremity peripheral artery disease. UptoDate. Accessed November 2020.

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