Arterial Ulcer Treatment

Understanding Severe Vascular Disease

Arterial ulcer treatment
Arterial ulcers are a serious and often debilitating condition resulting from poor blood flow due to peripheral artery disease (PAD) and other vascular issues. Characterized by painful, non-healing wounds typically found on the lower extremities, arterial ulcers can significantly impact an individual’s quality of life.

This article provides a comprehensive overview of arterial ulcers, including their symptoms, risk factors, diagnostic methods, and treatment options. By understanding the underlying causes and seeking timely intervention from a vascular specialist, individuals suffering from arterial ulcers can find effective ways to manage their condition and improve their overall health and well-being. Early diagnosis and appropriate treatment are crucial for preventing complications and promoting healing, making it essential for those affected to seek specialized care.

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Venous ulcer treatment specialist Dr. Michael Lalezarian in Los Angeles, California

Your Vascular Partner

Dr. Michael Lalezarian

Timely, accessible care is paramount in the effort against arterial ulcers, venous ulcers, and their complications.

Dr. Michael Lalezarian is a double-board certified Vascular Interventional Radiologist specializing in minimally invasive arterial leg ulcer treatment. He is a committed partner in the battle against the devastating consequences of advanced vascular disease.

5-star venous ulcer care in Los Angeles

“I cannot express enough the gratitude I have for Dr. Lalezarian and his entire staff. I came in for a ruptured vein on my ankle and Varicose veins to both of my legs. Each visit was met with extreme professionalism and care. Dr. Lalezarian, Jennifer, and the rest of the staff answered every question and concerns with compassion. I felt like I was in really good hands. Each procedure was painless with minimal recovery time. If you have any type of vein issues, I would highly recommend Dr. Lalezarian and his staff at ProVascularMD.”

John L, March 2022

Arterial Ulcer Causes

Arterial ulcers are caused by severe peripheral artery disease (PAD). Individuals with PAD experience plaque build-up in their arteries due to factors such as diabetes, obesity, high blood pressure, high cholesterol, smoking (nicotine constricts blood vessels), or other vascular diseases. This plaque accumulation and hardening of the arteries cause narrowing of medium and large arteries, limiting blood flow to the rest of the body. As a result, patients often experience muscle fatigue, leg pain, and cramping, commonly referred to as “intermittent claudication.”

As PAD worsens over time and becomes more severe, more of the arteries are affected and blood flow to the leg becomes insufficient, causing tissues to die due to the lack of oxygen. In turn, tissue death leads to ulcer formation. In many cases, an arterial ulcer persists until the underlying vascular issues are addressed.

Arterial ulcer causes diagram

Arterial Ulcer Risk Factors

Your arterial ulcer may be caused by one or more of the following risk factors:

  • Peripheral Artery Disease (PAD) – The primary risk factor, PAD, is caused by plaque build-up in the arteries, leading to reduced blood flow to the extremities.
  • Diabetes – High blood sugar levels can damage blood vessels and contribute to the development of arterial ulcers.
  • Smoking – Nicotine constricts blood vessels and accelerates plaque formation, significantly increasing the risk of arterial ulcers.
  • High Blood Pressure – Hypertension can damage arteries, making them more susceptible to plaque build-up and narrowing.
  • High Cholesterol – Elevated cholesterol levels contribute to plaque formation in the arteries, leading to decreased blood flow.
  • Obesity – Excess weight strains the cardiovascular system and can exacerbate other risk factors like diabetes and high blood pressure.
  • Older Age – Aging naturally leads to the hardening and narrowing of arteries, increasing the risk of PAD and arterial ulcers.
  • Vascular Diseases – Other vascular conditions can also increase the risk of developing arterial ulcers by affecting blood flow.

Understanding these risk factors is crucial for preventing arterial ulcers and managing existing conditions that contribute to their development. Despite the prevalence of these risk factors, the vascular component of arterial wounds is frequently underdiagnosed, leading many patients to live with arterial ulcers for months or even years before finding the right care.

Arterial ulcers on foot healing after treatment
Your Partner in Vascular Care
Venous Ulcer Treatment in Los Angeles

Arterial Ulcer Symptoms

If you have an arterial ulcer, you will likely experience both peripheral artery disease symptoms and ulcer symptoms. Arterial ulcers tend to develop in specific areas of the leg / foot and have a rather distinct appearance. The following signs and symptoms may indicate an arterial ulcer:

  • Leg Pain – The peripheral artery disease that causes arterial ulcers typically causes leg pain as well. PAD patients often describe an aching pain that worsens with activity and is relieved with rest, commonly referred to as intermittent claudication. In severe cases of peripheral artery disease, pain can persist even at rest.
  • Ulcer Location – Over time, poor blood flow leads to skin breakdown and ulcer formation. Arterial ulcers typically occur past the point of compromised blood supply, usually at the farthest parts of the body such as the feet, toes, fingers, legs, side of the ankle, and areas of pressure to the skin.
  • Ulcer Appearance – Arterial ulcers can be shallow or deep with sharp, “punched out” borders. The wound base is often pale grey or yellow and may be associated with gangrene and eschar (dry dark scab).
  • Surrounding Tissue Characteristics – Tissue surrounding the arterial ulcer may be itchy, pale, shiny, red, cold to the touch, and hairless.

Arterial Ulcer Diagnosis

Diagnosing arterial ulcers involves a thorough clinical evaluation by a healthcare professional, often a vascular specialist. The diagnostic process typically includes:

  • Medical History & Physical Examination – Your vascular specialist will begin by taking a detailed medical history, focusing on risk factors such as smoking, diabetes, high blood pressure, high cholesterol, and a history of peripheral artery disease (PAD). During the physical examination, the physician will assess the location, appearance, and characteristics of the ulcer, as well as the condition of the surrounding skin.
  • Ankle-Brachial Index (ABI) Test – This non-invasive test measures the blood pressure at the ankle and compares it to the blood pressure in the arm. A lower blood pressure in the ankle compared to the arm suggests reduced blood flow to the extremities, indicating PAD.
  • Doppler Ultrasound – This imaging technique uses sound waves to visualize blood flow in the arteries and identify any blockages or narrowing. It helps in assessing the severity and extent of the arterial disease.
  • Angiography – In more complex cases, an angiography may be performed. This involves injecting a contrast dye into the blood vessels and taking X-ray images to pinpoint the location and severity of arterial blockages.
  • Blood Tests – Blood tests may be conducted to check for underlying conditions such as diabetes, high cholesterol, and other factors contributing to poor arterial health.
  • Skin Biopsy – In rare cases, a small sample of skin tissue from the ulcer may be taken for laboratory analysis to rule out other causes of non-healing wounds, such as infections or malignancies.

By combining these diagnostic tools, the vascular specialists at ProVascularMD can accurately diagnose arterial ulcers and develop an effective treatment plan tailored to your specific needs. Early diagnosis and intervention are key to preventing complications and promoting healing.

Your Partner in Vascular Care

Venous Leg Ulcer Treatment in Los Angeles

Arterial Ulcer Treatment

Arterial ulcer treatment generally has three components: (1) manage peripheral artery disease risk factors to improve overall vascular health, (2) keep the ulcer clean and free of infection to allow healing, and (3) restore blood flow to the ulcerated tissue.

Lifestyle Changes & Medical Management

The initial focus of arterial ulcer treatment is on modifying peripheral artery disease risk factors through lifestyle changes and medications. Patients are counseled on smoking cessation, healthier dieting, and may be started on an exercise program. Medications can be used to manage risk factors, comorbidities, pain, and further artery obstruction. However, if your arterial ulcer is severe and you’re showing signs of advanced peripheral artery disease, your vascular specialist may urgently recommend an interventional procedure.

Arterial Wound Care

Patients with open, non-healing arterial wounds are typically referred to a wound care specialist who will clean the wound routinely and dress it with bandages to prevent infection and promote healing. Although wound dressing changes do not target the underlying arterial disease, arterial wound care is still an essential part of healing and complements other treatments.

Minimally Invasive Revascularization

For symptomatic disease, minimally invasive procedures are available to improve blood delivery past the arterial narrowing or blockage caused by peripheral artery disease. Revascularization aims to reestablish adequate blood flow through the artery so that ulcers can heal. Minimally invasive tools used for this purpose include atherectomy, angioplasty, and stenting. At ProVascularMD, we specialize in minimally invasive procedures for peripheral artery disease and arterial ulcers.

Surgical Options

For severe arterial disease that cannot be addressed with minimally invasive techniques, more invasive surgical options are available. These can include arterial bypass surgery, endarterectomy, and even amputation surgery in extreme cases.

Before & After Arterial Ulcer Treatment

The image below shows how minimally invasive revascularization can heal arterial ulcers by restoring blood flow to the affected area.

Before and after arterial ulcer treatment

Don’t Let Your Arterial Ulcer Go Untreated

If you’re living with an arterial ulcer, it is crucial to seek treatment from a vascular specialist. Arterial ulcers can significantly impact your quality of life, leading to persistent pain, non-healing wounds, and serious complications if left untreated. A vascular specialist can provide a comprehensive evaluation and tailor a treatment plan that addresses the underlying causes of your condition. Through lifestyle modifications, medications, minimally invasive procedures, and surgical options, a specialist can help restore blood flow, promote healing, and improve your overall well-being. Don’t let arterial ulcers go untreated—consult a vascular specialist today to take the first step towards recovery and a healthier future.

Your Partner in Vascular Care

Venous Leg Ulcer Treatment in Los Angeles

More Resources
Peripheral Artery Disease Screening: Why Early Detection is Critical in PAD

Peripheral Artery Disease Screening: Why Early Detection is Critical in PAD

PAD signs, symptoms, risk factors, and screening methods.
Endovascular Treatment of Lower Extremity Arterial Disease

Endovascular Treatment of
Lower Extremity Arterial Disease

A brief 101 on the treatment options available for arterial disease.
Los Angeles Vascular Specialist Dr. Michael Lalezarian

Vascular Specialist in Los Angeles

Learn more about Los Angeles Vascular Specialist Dr. Michael Lalezarian.


[1] Hedayati N, Carson JG, Chi Y-W, Link D. Management of mixed arterial venous lower extremity ulceration: A review. Vasc Med. 2015;20(5):479-486.
[2] Conte SM, Vale PR. Peripheral Arterial Disease. Heart, Lung and Circulation. 2018;27(4):427-432.
[3] Shu J, Santulli G. Update on peripheral artery disease: Epidemiology and evidence-based facts. Atherosclerosis. 2018;275:379-381.
[4] Salcrido, R. C. Arterial vs Venous Ulcers: Diagnosis and Treatment: Advances in Skin & Wound Care. 2001;14(3):146-147.
[5] Grey JE, Harding KG, Enoch S. Venous and arterial leg ulcers. BMJ. 2006;332(7537):347-350.

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